Datum Dental: Redefining Dental Bone and Tissue Regeneration
Daniel Levitats, Chief Commercial Officer
Despite various medical advancements made in oral care, the wear and tear of dental tissues from masticatory stresses, trauma or on-set of de-generative conditions such as periodontal disease may lead to bone and tissue loss, impacting daily function, ability to properly place implant and overall aesthetics. That said, in recent years, oral clinicians are using Guided Bone Regeneration (GBR) and Guided Tissue Regeneration (GTR) procedures to direct the growth of new bone and gingival tissue at sites with insufficient volumes or dimensions of bone or gingiva for proper function and prosthetic restoration. However, exposure to body fluids in the mouth can result in corrosion of the barrier membrane material and may react to release cytotoxic agents. ‘Oral clinicians worldwide are looking for less invasive materials that replicate the physiological properties of the original tissue and provide a long-term, predictable outcome,’ says Daniel Levitats, Chief Commercial Officer. The need of the hour is a material with the longevity and biological properties that enable proper tissue engineering (soft or bone), predictably and with high quality of bone-volume maintenance, while enhancing aesthetic outcomes.
This is where one company, Datum Dental, has been pioneering dental regenerative solutions for more than two decades to support and enhance the future of implantology and oral care. The company’s OSSIX® product family—powered by its patented GLYMTARTIX® core technology has been clinically proven to safely provide predictable, long-term results to patients in a wide range of GBR and GTR procedures. “We have been pioneering transformational solutions in the field of dental regeneration, to improve the ability of clinicians to produce superior outcomes in an effective and consistent way,” adds, Levitats.
Datum Dental’s proprietary GLYMATRIX® technology mimics the natural collagen cycle of a human body. This is achieved via utilizing tendons as a source material for highly biocompatible and safe collagen Type 1, applying a unique process to remove the telopeptides (immunogenic part of the collagen molecule sub-unit) and build a strong fiber network, and applying a natural biochemical process known as ‘glycation.’ By utilizing naturally occurring non-toxic sugar to cross-link the collagen fibers, Datum Dental’s GLYMATRIX® technology serves as the ideal core for OSSIX® regenerative solutions. This technologyis fully bio-programmable for precisely engineering long-lasting biomaterials (OSSIX® products) with enhanced stability and specialized properties suited for reconstructive and aesthetic medicine, enabling driving optimal results in terms of bone and tissue quality and quantity. General practitioners and specialists alike, can utilize these biomaterials to perform a broad array of GBR and GTR procedures efficiently, less invasively, while reducing post-treatment complications for the patient and overall treatment costs.
The OSSIX® portfolio comprises of OSSIX™ Bone (ossifying collagen sponge), OSSIX® Plus (ossifying collagen barrier membrane), and OSSIX® Volumax (volumizing hard and soft tissue remodellable scaffold).
We have been pioneering transformational solutions in the field of dental regeneration, to improve the ability of clinicians to produce superior outcome in an effective, less invasive and consistent way
Each of the three products were developed by Datum Dental to serve the requirements of various GBR and GTR procedures. A legacy product of the company, OSSIX® Plus is a novel ossifying collagen barrier membrane (serves as a true barrier for 4-6 months), that provides excellent biocompatibility and is resistant to degradation when exposed (for up to 3-5 weeks), improving soft tissue healing and minimizing complications or impact of patient non-compliance. OSSIX® Volumax, a unique volumizing, multi-layer collagen scaffold, was developed to help clinicians add extra volume mostly in lateral augmentations, buccal dehiscence, gingival recession procedures while having positive effect on bone and soft tissue quality. The latest innovation from Datum Dental, OSSIX™ Bone, is a resorbable hydroxyapatite and sugar cross-linked collagen matrix designed to promote natural bone regeneration without remnants or migration of material. All GLYMATRIX®-based OSSIX® products are manufactured in-house at Datum Dental’s 750 square meter GMP facility. The company adheres to stringent quality and ISO safety standards for its products with international regulatory clearances/approvals from CE, FDA, CGMP, and CMDR.
“With our products, patients are receiving a solution that has been tested and proven for over the last 20 years clinically to be less invasive while imitating the natural processes in our body,” explains Levitats. Datum Dental’s GLYMATRIX®-based products are trusted by tens of thousands of clinicians worldwide and covered by over 100 scientific publications. The company’s proprietary technology is a culmination of years of research into glycation as a cross-linking mechanism and offered through a global network of partners.
The unique features of OSSIX® products contribute to less repeated procedures and visits to the clinics, in general being extremely cost-effective in the long run of maintenance.
With significant breakthroughs being made in the field of tissue and bone regeneration, there are still major challenges to overcome before revolutionary treatment options can become mainstream. Datum Dental regularly collaborates with opinion leaders, researches, Universities and Educational Institutes, to deliver a broad range of educational activities (live webinars, hands-on workshops, lectures, live surgery, etc.) aimed at expanding the body of knowledge and best practices concerning regenerative dentistry solutions and surgical techniques. Currently, Datum Dental has its presence in over 40 countries via a broad network of global business partners, and is expected to grow to more countries by the end of 2021 geographically. For the future, the company aims to solidify its position as a leading regenerative company, by further developing and bringing to market new products for GBR and GTR that simplify procedures to overcome deficiencies in existing biomaterials through safe and transformational solutions. “We have several products in our pipeline that will continue to transform the space of dental regeneration and close existing gaps such as ease of use, reduce patient-chair time and enhance bone quality,” concludes Levitats.
Management Daniel Levitats, Chief Commercial Officer
Description Datum Dental, affiliated with Datum Biotech, uses its patented GLYMATRIX® core technology, a sugar cross-linking collagen biomaterial, for guided bone regeneration (GBR) and guided tissue regeneration (GTR) — clinically proven in over 100 scientific publications. Powered by GLYMATRIX, the OSSIX® product family has enabled clinicians in hundreds of thousands of procedures spanning almost two decades to safely provide predictable, long-term results to their patients.
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